Stat recruitment by tyrosine-phosphorylated cytokine receptors: An ordered reversible affinity-driven process
نویسندگان
چکیده
منابع مشابه
Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin.
The regulation of protein tyrosine phosphorylation is an important aspect during the cell cycle. From G2-M transition to mitotic anaphase, phosphorylation of Tyr421, Tyr466 and Tyr482 of cortactin, an actin-filament associated protein, is dramatically induced. The phosphorylated cortactin is almost exclusively associated with centrosomes or spindle poles during mitosis. At G2-M transition prior...
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For over a century, since the discovery by Roux and Yersin that sterile culture supernatants of Corynebacterium diphtheriae contained a potent toxin able to reproduce the lesions caused by diphtheria (1), most pathogenic bacteria have been considered to be microorganisms able to intoxicate local and distant tissues by secreting toxins in the ex-tracellular medium. Recently, it has been shown th...
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Tyrosine hydroxylase activity is reversibly controlled by the actions of several protein kinases. Previous studies showed that, following phosphorylation by protein kinase A, physiological concentrations of ascorbate irreversibly inactivate tyrosine hydroxylase. Several studies were performed to establish the mechanism of inactivation. We found that inactivation occurred under oxygen-free condi...
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ژورنال
عنوان ژورنال: Immunity
سال: 1995
ISSN: 1074-7613
DOI: 10.1016/1074-7613(95)90012-8